Transcranial Magnetic Stimulation (TMS) Therapy is cleared by the US Food and Drug Administration (FDA) for patients suffering from depression who have not achieved satisfactory improvement from prior antidepressant treatment. In 2010, the American Psychiatric Association recommended if an individual failed one antidepressant, TMS should be considered as equal a treatment option as changing to a different antidepressant.

TMS Therapy is performed at the TMS Serenity Center. Dr. Kimberly Cress and the TMS Team use the NeuroStar TMS Therapy system.

TMS Therapy is:

  • Performed at the TMS Serenity Center in Sugar Land, Texas by one of the most experienced TMS Therapy Care Teams in the United States.
  • Non-invasive, meaning that it does not involve surgery. It does not require any anesthesia or sedation, as the patient remains awake and alert during the treatment.
  • Non-systemic, meaning that it is not taken by mouth and does not circulate in the bloodstream throughout the body. Side effects frequently experienced from antidepressant medications i.e. weight gain, sexual dysfunction, tiredness, etc. do not occur with TMS therapy.

The TMS Serenity Center is Texas’ leading center for Transcranial Magnetic Stimulation. We are one of the few centers in the country and the first TMS center in Texas to publish our results.

To understand more about TMS therapy we recommend you visit the following by clicking each of the links below:

How Does TMS Therapy Work?

TMS Therapy generates a highly concentrated, magnetic field, which turns on and off very rapidly. This magnetic field is the same type and strength as that produced by a magnetic resonance imaging (MRI) machine.

Typically, the treatment coil is gently applied to the left front portion of the head. The magnetic field is focused on the left dorsolateral prefrontal cortex. This part of the brain is involved with mood regulation and is less active due to depression. This magnetic field does not directly affect the whole brain, only reaching about 2-3 centimeters into the brain directly beneath the treatment coil. As this magnetic field moves into the brain, it produces very small electrical currents. These electrical currents activate neurons within the brain which are thought to release neurotransmitters, like serotonin, norepinephrine, and dopamine to treat depression. These are the same neurotransmitters that are provided artificially through antidepressant medications. With TMS, we are able to provide these neurotransmitters directly.

spect-scanSPECT Scan1 (left)
These are images from a SPECT (single photon emission computed tomography) scan of the cumulative results from 12 men receiving TMS. The red-orange in these images show increases of blood flow in the brain as a result of TMS treatment. The bottom left image shows increased blood flow below the TMS coil. Other images also reveal increased blood flow in deeper brain regions involved in mood regulation and correlate with how TMS treats depression.


1. Kito, S, et al. “Changes in Regional Blood Flow After Repetitive Transcranial Magnetic Stimulation of the Left Dorsolateral Prefrontal Cortex in Treatment-Resistant Depression.” Journal of Neurosciences. 2008, 20: 74-80.